![]() ![]() TAGCHIMP METAZ MOVIE10 Disable automatic archiving.ġ Introduction What MetaX Does MetaX for Windows is a meta-data tagger for MP4 files and their derivatives, as well as QuickTime movie files. i think i am not the only one telling you it has replaced metax completely now. to announce that my tinkering has paid off and MetaX Mac is once again working with tagChimp :). MetaZ is an mp4 meta-data editor for OS X. (Linux/Mac OS X/Windows) Qt based frontend for a bunch of other tools which can. So i checked tagchimp and all the episodes are there - so i tried using the search faciltiy in metax but it woudnt find the episode Am i doing something wrong. It automatically gets data from sources like Amazon, tagChimp, TVDB and TMDB. It tagged a film for me perfectly, but when i tried to tag a episode from 'Black Books' it could only find one epsidoe from all three series. MetaX for Windows By KnowledgeDesign Software Updated ii Contents Introduction. tagChimp helps you easily tag your movies and TV shows. Also i have started using MetaX for windows. Example: barber Search MetaX for Windows - You can search TVDB, TMDB, tagChimp, Amazon and IMDB with the click of a. ![]()
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I'm writing this as I walk out the door for work so don't be offended if I don't respond right away to questions or comments but I will check back in tonight and of course be active here most days moving forward. #Infinifactory subreddit update#I've since re-modded /u/krispykrem, who is an official representative of Zachtronics, and will update his flair so new members to the community know he is an Infinifactory developer. #Infinifactory subreddit mod#Also if any graphically talented redditors would like to help out with this facelift please feel free to PM me and I can either give restricted mod permissions (for CSS changes) or accept Photoshop work for an updated banner.Īs some of you know from a previous thread there was a little confusion with /u/krispykrem (the previous sole moderator), and as I was out celebrating last night (Happy New Year by the way!) I didn't get to this until today. These two changes will make this place look more like an active community and less like an abandoned subreddit. I wanted to make a thread to poll some suggestions from the community regarding certain features or ideas you all think could improve this subreddit and make it a more attractive place for Infinifactory players. r/infinifactory: A subreddit for Infinifactory by Zachtronics. Now in Early Access Now in Early Access Lead the future of humanity and harness the power of stars by building the first Dyson Sphere in the whole galaxy 37.9k Engineers 96 Working Created Oct 15, 2020. #Infinifactory subreddit plus#Like you I love the Infinifactory game and am looking forward to livening this place up a bit! INFINIFACTORY FORUM PLUS SpaceChem starts out simple but gets hard FAST. The Official subreddit for Dyson Sphere Program, a sci-fi management game by Youthcat Games and Gamera Game. Right-click to download.Hey everyone! My name is Flope and I've recently become a moderator for this sub. ![]() Logo by Aaron Perry-Zucker, using Icons by by Llisole, Dávid Gladiš, Atif Arshad, Daniel Nochta, Mike Rowe, Jakub Čaja, Raji Purcell and IconsGhost from the Noun Project. french provincial living room furniture mobile legends port list 2021. You can also subscribe using good old-fashioned RSS. We’re on Apple Podcasts, Stitcher, Google Podcasts, Spotify, PocketCasts, Overcast, Breaker, and RadioPublic. If anyone else who doesn't have a reddit account wants to post here, please follow the formatting guidelines I have listed there. I'll try to watch this thread for at least the next few days, but it really would be easier for me to watch just 1 thread. “Reflection” and “Unease” from the Eliza Original Soundtrack by Matthew Seiji Burns. I broke down to compete in the Infinifactory weekly challenge. “All The People Say (Season 3)” by Holly Hyperion. ![]() #Infinifactory subreddit full#Full disclosure, for those who consider saying nice things about a video game to be the most sacred of trusts: I did some testing/proofreading/incredibly minor script consulting for Eliza.And here’s Matthew’s game The Arboretum.Homosexuality became officially not-a-pathology in 1973.What the hell was I thinking when I said Donna Haraway? “Manifesto for Cyborgs,” probably, since that’s relevant to Eliza for other, gender-and-tech reasons. It was Arlie Russell Hochschild who first talked about emotional labor, most famously in The Managed Heart.Here’s the web-based version of the original Eliza.I’ll Build a Stairway to Paradise by George and Ira Gershwin, performed by Richard Glazier. And The Zachtronics Podcast really is off to a rollicking start. for helping me get my thoughts together on this game. The Infinifactory subreddit really is a thing of wonder. You Can Feel Great All The Time Solving Problems A Pseudo-Instruction That Has No Effectģ4. On the Semi-Unspoilability of InfinifactoryĢ1. ![]() You can also follow Matthew on Twitter, and discuss Eliza on its dedicated subreddit.Īnd if you want to hear way more about Zachtronics, here are the episodes featuring the one and only Zach Barth:ġ9. You can get Eliza on Steam, Itch, GOG, and Humble. It’s a game about human connections, moral responsibility, burnout, and the problems that technology and futurism are ill-equipped to solve. Instead we focus on Eliza, the new Zachtronics-published visual novel that finally puts his writing (and to a lesser, though significant degree, his audio) front and center. In this interview, we talk about basically none of those. Matthew Seiji Burns is responsible for some of the best and least-discussed narratives and soundtracks in games, namely those in the beloved-for-other-reasons Zachtronics works Infinifactory, TIS-100, SHENZHEN I/O, and Opus Magnum-not to mention the generally under-discussed Where the Water Tastes Like Wine, his Twine work, and his past-life AAA work on the Call of Duty, Halo, and Destiny series. ![]() ![]() ![]() In the preclinical setting, the DXd-ADC technology has been effective when applied to target other cancer-associated antigens as well ( 10–12). These features enable the wide therapeutic window of the ADC with high antitumor potency and less systemic toxicity ( 9). ![]() The DXd-ADC technology has desirable characteristics for ADC including a highly potent payload (DXd) with a short systemic half-life, a cleavable linker designed to be tumor selective which is stable in circulation, and an average drug-to-antibody ratio (DAR) up to 8 being optimized for each target. Trastuzumab deruxtecan has received an accelerated approval from FDA and PMDA for patients with unresectable or metastatic HER2-positive breast cancer who have received two or more prior anti-HER2-based regimens in the metastatic setting. Trastuzumab deruxtecan (ENHERTU, T-DXd, DS-8201), a novel HER2-directed ADC with this DXd-ADC technology, demonstrated potent antitumor activity with acceptable safety profiles in preclinical models and patients with HER2-positive cancers ( 2, 4–8). Recently, we developed a novel ADC technology platform with a novel DNA topoisomerase I (Topo I) inhibitor, DXd, and a cleavable tetrapeptide-based linker ( 2, 3). These results suggest Dato-DXd could be a valuable treatment option for patients with TROP2-expressing tumors in the clinical setting. Safety profiles of Dato-DXd in rats and cynomolgus monkeys were acceptable.ĭato-DXd demonstrated potent antitumor activity against TROP2-expressing tumors by efficient payload delivery into tumors and acceptable safety profiles in preclinical models. Dato-DXd also showed potent antitumor activity with tumor regression in several TROP2-expressing xenograft tumors including NSCLC PDX models. Dato-DXd exhibited in vivo antitumor activity with DNA damage induced by the accumulated DXd in TROP2-expressing xenograft tumors, but neither isotype control IgG-ADC nor anti-TROP2 antibody had this effect. Safety profiles were also assessed in rats and cynomolgus monkeys.ĭato-DXd bound specifically to TROP2 and was internalized into tumor cells followed by intracellular trafficking to lysosome and DXd release, which induced DNA damage and apoptosis in TROP2-expressing tumor cells in vitro. ![]() The pharmacologic activity and mechanism of action of Dato-DXd were investigated in several human cancer cell lines and xenograft mouse models including patient-derived xenograft (PDX) models. We developed the novel TROP2-directed antibody–drug conjugate (ADC), datopotamab deruxtecan (Dato-DXd, DS-1062a), with a potent DNA topoisomerase I inhibitor (DXd), and evaluated its antitumor activity and safety profiles in preclinical models. Trophoblast cell surface antigen 2 (TROP2) is highly expressed on various epithelial tumors and correlates with poor prognosis. ![]() ![]() ![]() Depending on the characters you have chosen and the items in the room, different interesting things will happen. ![]() You will also be able to pick four characters among Lincoln and at the bottom of the screen, you will see the choices you can make. The Bomb Maker The Butcher The Doll Maker The Loogaroo Warehouse 33 Weed Post zeroDAY 10 PM - 1 AM Black Hat Post Euro Firearms Organ Mart Tango Down The Muhgel 10 PM - 2 AM Burned at the Stake 11 PM - 2 AM Nude Youtubers The Prey 11 PM - 3 AM Grave Thieves 12 AM - 3 AM Doctor Murder Shadow Web Portal Testical Mutilation 12 AM onwards Father. This game is here to introduce the characters to you and now you will find more stuff about Lincoln, the main character, who lives in a house with ten sisters.įirst of all, you will be able to choose between three rooms in which you can play: the living room, Lori and Leni's room, and Lincoln's room. Pick from BB's favorite themes and dress up your L.O.L. Surprise balls to unbox - expand your collection and have fun with BBs DRESS UP AND TAKE CUTE PICTURES. ![]() We are sure you are going to enjoy playing these games because they are all fun to play. Surprise dolls - each of them unique and fabulous, cute but fierce Find clues, play cool mini games, collect diamonds and get new L.O.L. Welcome to the game 2 doll maker with nudity tv#Welcome to the Loud House is a new game that we have added to our The Loud House Games category, a truly lovely and special category of games because it brings together the amazing characters from the TV show called The Loud House. ![]() ![]() ![]() Our season will conclude with ecstasies and explorations of the human psyche, featuring the posthumous world premiere of The Elemental Prayer Suite by Carl St. The program will feature the West Coast premiere of Seven Decisions of Gandhi by composer, violin soloist, and Cultures in Harmony founder William Harvey. ![]() Juxtapositions of heroic journeys by Gandhi and Beethoven will be presented in our April program, with works symbolizing their singular evolutions and triumphs of will. In January, we will present the world premiere of a new piano concerto by Turkish composer and pianist Hakan Ali Toker, commissioned specifically for the Santa Cruz Symphony, in a program also featuring vivid translations of Point Reyes wildlife by Northern California native Gabriella Smith, and Ravel’s homage to the Parisian Baroque à la François Couperin. Our October program is dedicated to testaments to courage, resolve, and the endurance of the human spirit told through music, featuring the final works of Tchaikovsky and Bartok, a prayer for Ukraine, and viola soloist Yuchen Lu. Our celebratory 65th season begins in September with thrillingly grand symphonic treatments of folkloric dances from across the world including Slavonic, Chinese, Rumanian, Hungarian, South African, and Mexican traditions, featuring a special collaboration with Watsonville’s own Esperanza del Valle Baile Folclórico. MUSIC THAT ILLUMINATES the indescribable, the breathtaking, the unforgettable ![]() ![]() ![]() Sind sie in diesem Fall während des Seitenbesuchs unserer Webseite bei Google eingeloggt, verwendet Google Ihre Daten zusammen mit Google Analytics-Daten, um Zielgruppenlisten für geräteübergreifendes Remarketing zu erstellen und zu definieren. Zu diesem Zweck setzt Google ein Cookie im Browser Ihres Endgeräts, welches automatisch mittels einer pseudonymen Cookie-ID und auf Grundlage der von Ihnen besuchten Seiten eine interessensbasierte Werbung ermöglicht.Įine darüberhinausgehende Datenverarbeitung findet nur statt, sofern Sie gegenüber Google zugestimmt haben, dass Ihr Internet- und App-Browserverlauf von Google mit ihrem Google-Konto verknüpft wird und Informationen aus ihrem Google-Konto zum Personalisieren von Anzeigen verwendet werden, die sie im Web betrachten. Anbieter ist die Google Ireland Limited, Gordon House, 4 Barrow St, Dublin, D04 E5W5, Irland (“Google”). 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![]() ![]() Above him is Rainbow Power, which was able to easily defeat Tirek, and is the strongest power in the show currently. Lord Tirek, at his peak, is immensely powerful, with the power of all 4 Alicorns, every other pony in Equestria, and even Discord. Flurry Heart when her power fluctuated was able to destroy the Crystal Heart. ![]() The Crystal Heart is another powerful artifact that is at least powerful enough to neutralize Sombra's magic and even kill him while in a weakened form. The Pony of Shadows is also a powerful entity, able to survive being hit with the Elements of Harmony. However, even they are taken down by the Elements of Harmony, which are shown to be able to defeat all of the villains seen above, proving them to have power far greater than these villains, or at least neutralizing "evil" characters and they scale to their human counterparts. Discord is next, who is able to take blasts from the likes of Sombra, showing even higher levels of Solar System level via scaling and even has a few claims to affect all of reality with his magic. Lower tier top tiers such as Twilight Sparkle, Starlight Glimmer, potentially Trixie with the Alicorn Amulet, Starswirl, and more scale to beneath that, due to Starswirl replicating Celestia's feat with 5 Unicorns every day. These characters are contested by the Dazzlings, Queen Chrysalis with a plethora of love absorbed, and Sombra who have shown power comparable or even superior to that of 1 Alicorn. Small Country level characters come next, with the likes of the Mane 6, Trixie Lulamoon, and Adult Spike, coming from Rainbow Dash's Sonic Rainboom.Īfter that, we have a gigantic power leap with the likes of Celestia and Luna, who breach outright Solar System levels of power for being able to easily move both the Sun at near lightspeed. The verse's characters start out at roughly Wall level with fodder, before kicking it up to at least Multi-City Block level with some of the lower tiers such as Spike the Dragon. The show is highly popular nowadays due to its large male following in addition to female, and has become one of the most popular cartoons airing today. They have battled many enemies along the way, such as Night Mare Moon, Discord, Queen Chrysalis, King Sombra and Lord Tirek, and have used the legendary Elements of Harmony and newly discovered Rainbow Power to defeat them. ![]() The show follows Twilight Sparkle on her journey to discover the magic of friendship and make friends with 5 other ponies: Rainbow Dash, Applejack, Fluttershy, Rarity and Pinkie Pie. The franchise My Little Pony is split up into 4 Generations, with the most popular and most powerful being that of Generation 4, Friendship is Magic. ![]() ![]() ![]() What concerned them most was the absence, dysfunction, or loss of social connections. People described their regrets about relationships much more intensely than those about careers and other nonsocial aspects of their lives. (Regrets about financial missteps rank just below these love and work regrets.) My research with Mike Morrison and Kai Epstude, for example, surveyed over 1,300 people across five studies and found that people’s largest regrets revolved around relationships and career. Psychological research has examined what adults tend to regret later in life, and there is a clear pattern of top regrets centering on love and work - that is, romantic, family, and friend relationships on the one hand and career, work, and education on the other hand. The problem becomes all too clear when you look at how regretful people tend to feel about losing touch with friends. In a recent meta-analysis of 148 studies, having strong social relationships was associated with a 50% reduction in risk of mortality.īut maintaining close friendships is increasingly a challenge for ambitious professionals. We are less likely to catch a cold or suffer from acute stress responses if we have a solid network of friends. And beyond the psychological benefits, friendships can influence our basic physiology, as shown by studies that link social connections to cellular-level protection against disease. The number and strength of our friendships has long been a consistent predictor of emotional well-being. These people are critical for both our psychological and physical well-being. Psychologists define close friends as those nonrelatives whose birthdays we celebrate, with whom we discuss intimate matters such as work or marital stress, and whom we might call upon for help with a move or a medical emergency. ![]() Basic research tells us this is so, yet many who focus on their careers run the risk of losing touch with their closest social connections. Everything we do to succeed in our careers is improved when we’re supported by a foundation of strong, stable friendships. ![]() |
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